Introducing a new category: Health Signal Intelligence

Introducing the world's first
real-time prediction
system powered by
voice & vital signs

We turn everyday health signals—voice and vital signs—into early insights that help clinicians stay ahead of patient deterioration.

Initial focus: early detection of patient deterioration between visits and after discharge — starting with primary care.

Health signals have always told a story.
We listen.

Predicate AI Labs was founded on a simple insight: the human body signals deterioration long before it becomes clinically visible.

Our platform captures continuous voice and vital sign data, transforming it into time-aligned signals that reveal subtle physiological change.

Powered by our proprietary OpenDx™ engine, we detect patterns of health deterioration earlier—enabling clinicians to intervene before conditions escalate.

This is not another dashboard. It’s a new layer of clinical intelligence.

98%
sensitivity in identifying true sepsis
Prospective emergency department triage cohort (n=270) using voice-derived features in a low-resource setting

Clinical validation expanding across multiple geographies and care settings

//  DATA INPUTS
Multimodal. Continuous. Patient-specific.
Voice Signals
Your voice as a physiological sensor. Detecting subtle changes in health through speech.
Vital Signals
Continuous physiological monitoring. HR, RR, Temp, SpO₂ from any connected device.
Time-Aligned Data
Signals synchronized across modalities. Capturing change as it happens.
Contextual Data
Clinical history, medications, labs. Used to enhance signal interpretation.
//  CORE PROCESSING
AI
OpenDx™
Core Engine
1Data Fusion
2Pattern Mapping
3Risk Prediction

Platform

How It Works: From Signal to Early Insight

A real-time signal intelligence pipeline that transforms raw physiological data into early indicators of patient deterioration.

Multimodal inputs. Time-aligned. Continuously learned.

Signal Inputs
Vital Sign Streams
HR, HRV, RR, SpO₂, Temp — any wearable
Voice Features
Acoustic, prosodic & linguistic
Continuous Metabolic Monitoring
CGM data
Health History
Medications & labs
Signal Processing
Noise Filtering
Adaptive artifact removal
Feature Extraction
Acoustic, linguistic, and physiological signals
Temporal Alignment
Multi-modal sync engine
AI Engine
Baseline Modeling
Learns patient-specific physiological norms over time
Deviation Detection
Identifies subtle changes from baseline before clinical thresholds
Predictive Signal Mapping
Translates patterns into early indicators of deterioration
Clinical Output
Real-Time Signals
Priority-ranked indicators of patient deterioration
Clinical Escalation Support
Risk-tiered guidance for timely intervention
Explainability Layer
Transparent signal attribution for clinician trust
Population Insights
System-wide visibility into patient risk trends

Where We Start

One problem.
One high-impact setting.

We are initially focused on one high-impact problem: identifying early signs of patient deterioration outside the hospital setting.

Starting with general practice / primary care, our platform enables clinicians to monitor patients between visits—when deterioration often goes unnoticed.

This creates a new standard of proactive care: continuous awareness without added clinical burden.


Team

The people behind the platform

Built at the intersection of clinical medicine, signal processing, and AI systems engineering

Morris Nguyen
Morris Nguyen, MD, MBA
Founder & CEO
Tech humanitarian, physician-entrepreneur, and architect of OpenDx™, a multimodal AI platform that fuses voice and physiological signals to detect early signs of patient deterioration before they become clinically apparent.
Dana Xiadani
Dana Xiadani
Head of Speech Engineering & Intelligence
Signal processing engineer specializing in vocal biomarkers. Leads development of voice-based models for detecting early physiological and cognitive change.
Ryan Roberts
Ryan Roberts
Chief Technology Officer
Product and systems architect with experience building enterprise-grade platforms. Leads development of scalable, real-time multimodal infrastructure.
Sunil Desai
Sunil Desai, MD
Chief Medical Officer
Intensivist and senior health system executive. Former Chief Physician Executive of Orlando Health, CMO of Presence Health TeleICU, and CMO of CHRISTUS Health. Provides clinical oversight and health system integration.
Kathryn Roberts
Kathryn Roberts
Chief Operating Officer
Founder & CEO of The Bluewater Group. 34 years in manufacturing operations, supply chain, and business systems. Brings deep expertise in operational execution and scalable implementation.
Gerald Maccioli
Gerald Maccioli, MD, MBA
Chief Strategy Officer
Critical care anesthesiologist with 36 years of clinical practice. Former CMO of HHS Technology Group and Chief Quality Officer of Envision Healthcare. Named by Becker’s as one of 50 experts leading patient safety.

Clinical Validation & Partnerships

All news →
Press Release
Predicate Announces Collaboration with Mayo Clinic to Advance AI-Powered Early Detection of Sepsis
Research
From Prediction to Practice: Clinical Validation of Vocal Biomarkers Within a Population-Specific Multimodal Risk Architecture
Partnership
Predicate partners with the top three medical institutions in India for Phase I prospective validation